Limb ischaemia after intra-arterial injection of Temazepam gel: histology of nine cases.
نویسندگان
چکیده
منابع مشابه
Limb ischaemia after intra-arterial injection of Temazepam gel: histology of nine cases.
AIMS To record the histopathological findings associated with intra-arterial injection of Temazepam gel by nine drug misusers. METHODS Standard histological examination and immunocytochemistry for endothelial markers (factor VIII related antigen, Ulex europaeus lectin) were carried out. RESULTS Intra-arterial injection of Temazepam gel may cause severe vascular injury and lead to amputation...
متن کاملAggressive management of intra-arterial Temazepam injection.
Intravenous injection of the oral formulation of Temazepam is a common form of drug abuse. At the request of the Home Office, manufacturers have developed solid dose forms to replace the liquid filled capsules, but a number of cases of accidental intra-arterial injection of the new formulation have been reported, with varying management strategies advocated. A case is presented where prompt agg...
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Renal transplantation is considered one of the best long-term therapies for chronic renal failure, but unfortunately the incidence of malignancy significantly increases in renal transplant recipients. We analyzed nine cases of malignancy in 200 renal transplant recipients occurring in a 12-year follow-up in Imam hospital of Tehran University, Tehran, Iran. According to this study, the organ...
متن کاملGood clinical outcome after accidental intra-arterial injection of flunitrazepam tablets in 16 drug abusers with critical limb ischaemia.
OBJECTIVES Inadvertent intra-arterial injection of flunitrazepam tablets intended for intravenous use by drug abusers has devastating effects. We report here on the clinical outcome of 16 drug abusers developing critical limb ischaemia after flunitrazepam injection. METHODS Treatment combined immediate analgesia and anticoagulation, long-lasting local thrombolysis and vasodilatation, antibiot...
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Accidental intra-arterial injection of intramuscular antibiotic preparations is described in 3 cases in infants. In 2 benzathine penicillin was injected, and in 1 rolitetracycline. The clinical features are dominated by arteriolar obstruction which produces gangrene of the most severely affected limb. In addition, neuroloigcal involvement occurs when vessels to nerves or spinal cord are involve...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1994
ISSN: 0021-9746
DOI: 10.1136/jcp.47.6.512